Welcome to our website describing recent efforts at Case!
Our laboratory’s contributions to the fields of bioorganic chemistry and natural product biosynthesis are focused on building two synergistic platforms: a. designing novel strategies for explicating nature's construction of natural products and b. discovery of new biocatalytic systems. For a visual representation, see cartoon at the bottom of the page. We strive to accomplish these goals in a green, economic and sustainable fashion by unraveling nature's biosynthesis potential. Using tools such as genomics, organic synthesis, mechanistic enzymology, and microbiology we design platforms that delineate bioorganic mechanisms of medicinally-important and structurally complex natural product biosynthesis. As an application of our research strategies, we construct biosensors, study the modulation of human enzymes and mammalian siderophore biosynthesis.
Projects currently underway in the Viswanathan group involve:
Natural Product Biosynthetic Pathways from Microbial Niches
Biosensors for Catalysis and Detection of Metabolites
Modulation and Biomimicry of Enzymes through Organic Chemistry
Mammalian Siderophore Biosynthesis
Concomitantly with research projects, our group leads outreach activities that engage students from Cuyahoga Community College and Cleveland Metropolitan School District High schools. Please click here for more outreach information.
Currently, there are no post-doctoral positions available in the Viswanathan Lab.
If interested in pursuing your graduate study (toward a Ph. D. or M.S. degree) at CWRU, please click here for Case Chemistry graduate program.
If you are an undergraduate student and are interested in the Capstone projects, please click here to learn about opportunities.
Do you have any feedback about this site?
This site is regularly updated by Brittney Bunn, a graduate student in the Viswanathan group. Please contact Brittney at firstname.lastname@example.org if you need additional information. Your comments are welcome and appreciated.